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[ Recent studies have indicated that UA acts as an endogenous danger signal and at the same time triggers NOD-like receptor protein 3-dependent inflammation

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To be specific, deletion of GPX4 in T cells resulted in loss of Tfh cells and GC responses in immunized mice, suggesting that Tfh cells are particularly susceptible to ferroptosis

These considerations are educational and are not a substitute for individualized medical advice

Among them, -3 polyunsaturated fatty acids and polyphenols are important components of anti-inflammatory diets, while collagen peptides, vitamin D, calcium, probiotics, glucosamine, chondroitin and hyaluronic acid are commonly used in clinical practice as important nutritional support treatments or preventive measures for OA to promote cartilage repair