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Tsuji-Naito et al 27 demonstrated that DHLHZn (sodium zinc dihydrolipoyl histidinate, compound of Zn2+/dyhydrolipoic acid derivative complex, which was developed for cosmetic/medical use) serves as a potentially effective skin-lightening agent, an effectiveness that is based on the compounds covalent scavenging of DOPAquinone, resulting in depigmentation

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The difference is substantial but not insurmountable

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Zoa AB, Yang Y-j, Huang W-j, Ndoadoumgue AL, Tian Y-t (2022) The role of short peptides in tumor angiogenesis

The TEM images (Fig