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However, clinical trials of emphysema patients with and without AATD have failed to demonstrate measurable improvements in lung destruction

The reverse cholesterol transport (RCT) pathway involving high-density lipoprotein (HDL) is an important process to maintain the balance of cholesterol metabolism, and promotes the efflux of free cholesterol from macrophages (63)

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This may restore ovulatory function in PCOS but could also disrupt luteal function upon abrupt withdrawal

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