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Given the questionable observations in the studies and the unclear mechanisms of action, it is currently not recommended to use or attempt GLP-1 receptor agonists in clinical settings for PD outside of research contexts

Retatrutide is currently an investigational triple-agonist medication being studied for obesity and metabolic health

Expensive medication, poor results, mounting frustration

There are a few different kinds, but the group getting the most attention right now is called GLP 1 medications

Appetite reduction is often felt within the first week

Septernas preclinical data showed that combining its oral GIP receptor agonist with semaglutide produced tirzepatide-like weight loss in mice