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doi: 10.1001/archinte.167.11.1145
The SUSTAIN-2 clinical trial compared semaglutide 0.5 and 1.0 mg with sitagliptin 100 mg over the course of 56 weeks in patients with T2DM inadequately controlled with metformin, thiazolidinediones or both
By activating certain neurons in the hypothalamus, semaglutide can decrease hunger, increase feelings of fullness, and reduce or eliminate cravings, further promoting weight loss
"Our new analyses provide assurance that the medication, when taken by individuals who are free of significant mental health concerns, does not increase the risk of depression, suicidal thoughts, or suicidal behavior," said lead author Professor Thomas A
4.1.5.2 In vitro testing Several attempts have been made to develop in vitro methods for testing contact sensitization (von Blomberg et al., 1990