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An important theoretical concern exists: c-Met is overexpressed in multiple human cancers (gastric, lung, colorectal), and chronic c-Met pathway stimulation could potentially influence cancer riskthough this has not been studied longitudinally even in animals

Rationale and study design of a randomized, placebo-controlled, double-blind phase 2b trial to evaluate efficacy, safety, and tolerability of an oral glutaminyl cyclase inhibitor varoglutamstat (PQ912) in study participants with MCI and mild AD-VIVIAD

5-Amino-1MQ is a small molecule, which has different research-design implications: Different stability profile

So the ban was never proof that it works

DOI: 10.1046/j.1523-1755.63

Taggart C, Cervantes-Laurean D, Kim G, et al