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Biochemically it serves two enzymes: methionine synthase, which remethylates homocysteine to methionine and regenerates the cells methyl-donor pool, and methylmalonyl-CoA mutase in mitochondrial energy metabolism[1][2]

Berberine is a natural GLP-1 booster that helps curb cravings, improve insulin sensitivity, and support hormone balance, without the needles or harsh side effects

Furthermore, 10 mM keto--methylvaleric acid (KMV) was used as a control to demonstrate complete inhibition of the OGDHc in vitro

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