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(adapted) Jastreboff AM, et al

Serious but rare side effects include pancreatitis (0.3%), gallbladder events (1.4%), and acute kidney injury associated with dehydration (0.7%)

Who Should Avoid Abrupt Cessation and Why Provider Input Matters Patients with a history of rapid weight regain, binge-eating patterns, or metabolic syndrome face higher rebound risk and should never stop semaglutide without medical oversight

In the testes, GPx4 reduces phospholipid hydroperoxides, hence protecting immature spermatozoa cells against oxidative stress

Srivastava et al., 2024)

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