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To add more complexity, studies should also include functional assays using low doses of MNPs, which can modulate cellular homeostasis without evident cytotoxic effect

These signaling pathways are analyzed in vitro to evaluate their role in cellular communication, transcriptional regulation, and protein synthesis processes

[Google Scholar] Gugumus F, Gachter R, Muller H, editors

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Such models are invaluable for optimizing therapeutic outcomes while minimizing off-target effects (Takemura et al., 2020)

This FDA approval is based on the results of the SURMOUNT-OSA phase 3 clinical trials