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Over the last several months, we have conducted detailed reviews of reports of suicidal thoughts or actions received in the FDA Adverse Event Reporting System

Brain MRI reveals several abnormalities in patients with cerebral folate deficiency, including delayed myelin development, cerebellar atrophy, cortical laminar necrosis, bilateral intrabasal ganglia calcifications, frontal lobe and cerebellar atrophy

Clin Chim Acta 90(1):3743

Mutations of any of these residues reduces GPX4 activity