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Hydroxychloroquine, the active ingredient in Plaquenil, is not effective against all strains of malaria, or against malaria in areas where the infection has been resistant to a similar drug called chloroquine 1

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It also examines the short- and long-term effects of treatment on apoptosis, inflammation, and regeneration in the spinal cord trauma zone

For many individuals, digestive symptoms are most noticeable: during the first few weeks, after dose increases, or after eating large high-fat meals

BMC Genomics 21:145