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While there is no definitive evidence that Vitamin B12 injections directly cause weight loss, they can support your weight loss journey in other ways

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Since the FDA has not approved Wegovy specifically for insulin resistance, using it for this purpose would be considered off-label

However, there are meaningful health risks from the weight regain and metabolic changes that follow: worsening blood sugar control in prediabetes or type 2 diabetes, increased cardiovascular risk, return of obesity-related conditions, and psychological impact from regaining lost progress