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Table 4 summarizes potential therapeutic strategies targeting bile acid signaling and gut microbiota, including probiotics, prebiotics, fecal microbiota transplantation, bile acid analogs, and selective FXR/TGR5 agonists and antagonists

Orforglipron also reportedly has a simpler production process than injected GLP-1 drugs such as Ozempic and tirzepatide (sold as Mounjaro) and does not require cold storage factors that could help improve access to the drug if it is approved for use

Why Are Patients Filing Lawsuits Over Ozempic and Similar GLP-1 Drugs

Women who may become pregnant should discuss contraception with their physician before starting semaglutide

Benoist CC, Kawas LH, Zhu M, Tyson KA, Stillmaker L, et al

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