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Further research is needed to understand how the composition of intestinal microbiota influences the metabolic fate of ingested choline

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In recent research articles, new drugs such as GLP-1 (glucagon-like peptide-1 receptor agonists), SGLT2 (sodium-glucose cotransporter-2 inhibitors) and RAAS (renin-angiotensin-aldosterone system inhibitors) have been found to slow down the progression of DKD (110, 111)

That doesnt mean its useless

It cant just be because Im eating much less, because I havent reduced my caloric intake that much