Previous assumptions held that these medications wouldnt directly affect liver enzymes since GLP-1 receptors arent present in significant quantities on hepatocytes (liver cells)
While BMI is an important starting point for eligibility, a comprehensive approach is taken, considering factors like existing medical conditions, medication interactions, dietary habits, physical activity levels, and individual health goals
Current Medical Research and Opinion, 33 (7), 1191-1197
Although not approved specifically for PCOS, GLP-1 RA use in women with PCOS has been associated with improved blood glucose control and weight loss, as well as improvements in menstrual regularity and a decrease in ovarian cysts ( 4 , 6 8 )
Benefit of semaglutide in symptomatic peripheral artery disease by baseline type 2 diabetes characteristics: insights from STRIDE, a randomized, placebo-controlled, double-blind trial
Commonly reported side effects include: Nausea and vomiting Diarrhea or constipation Decreased appetite In some cases, more serious health concerns have been reported, including: Gastroparesis (Stomach Paralysis) A condition where the stomach empties food very slowly or stops functioning properly, potentially causing severe nausea, vomiting, bloating, abdominal pain, and difficulty eating