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By brightening the skin some tyrosinase inhibitors brighten the skin and make it look more radiant, luminous, and healthy

Electrophysiological recordings demonstrate that Dihexa-treated neurons exhibit significantly increased frequency of miniature excitatory postsynaptic currents (mEPSCs), indicating enhanced synaptic transmission

It is diagnosed through skin biopsy showing reduced intraepidermal nerve fiber density (IENFD) or corneal confocal microscopy showing reduced corneal nerve fiber density

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In some embodiments, the otic formulation or composition comprises about 15% by weight of the povidone

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