Potential effects on methylation pathways and NAD+ metabolism should be considered
Vitamin B12 deficiency affects many of your bodys vital systems including neurological, hematologic, immunologic, vascular, gastrointestinal, musculoskeletal and genitourinary
Not diet-related If your vitamin B12 deficiency is not caused by a lack of vitamin B12 in your diet, youll usually need to have an injection of hydroxocobalamin every 2 to 3 months for the rest of your life
Individuals with MTHFR variants may rely more heavily on active B12 forms like methylcobalamin or adenosylcobalamin, depending on methylation response
GLP-1RAs in nervous system In the nervous system, GLP-1 can decrease oxidative stress and inflammatory responses, potentially through reducing the generation of ROS and decreasing the expression of inflammatory cytokines
Temporary hair shedding affects about 5-8% of people taking Retatrutide, typically starting 3-4 months into treatment