In PCOS, NAC also supports healthy insulin levels, decreases total testosterone, and increases follicle-stimulating hormone (FSH), a hormone involved in ovulation
In the reactions of protection against ROS, the role of glutathione is illustrated by the reduction of peroxides: R = H or alkyl group, and by the neutralization of free radicals: GSH takes part also in the reduction of protein disulfides (PrSSG) catalyzed by glutaredoxins (GRXs)
A pilot study evaluating the effect of a 28-day VLEKT on clinical HS severity in 12 overweight and obese women revealed weight loss and a reduction in HS severity as measured by the Sartorius score (216)
Am J Biochem Biotechnol/Am J Biochem Biotechnol 4(2):73
The study concluded that long-term antioxidant therapy with NAC helped prevent the development of pre-diabetes, dyslipidemia, and liver inflammation in obese rats, largely by reducing oxidative stress
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