The half-life of GIP is 5 to 7 min [28], since it is rapidly inactivated by the ubiquitous enzyme dipeptidyl peptidase 4 (DPP-4) [29] that cuts alanine and proline residues in position 2 of the N-terminus in peptide chains [30]
was supported by a MOBILITAS Postdoctoral Research Grant (MJD252)
[9] Diamond LE, Earle DC, Rosen RC, Willett MS, Molinoff PB
Although there are no randomized controlled trials comparing aromatase inhibitors with traditional medical therapy for endometriosis, pilot studies using aromatase inhibitors with add-back progestins or OCPs have demonstrated significant reduction in endometriosis-associated pelvic pain (37)
A large, rigorous, clearly negative trial is not a wasted trial
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