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Continuous use can blunt growth hormone response, leading to reduced sleep benefits, stalled fat loss, and lower IGF-1 levels

If it is less than 130 mg/dL and the pre-dinner blood glucose level is still not at the target, adding a third injection of pre-mixed insulin before lunch should be considered, starting with 6 units and titrating weekly based on pre-dinner blood glucose levels [47]

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Editor's Note Fight signs of aging and uneven skin tone with this moisturizing face cream