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doi: 10.1007/978-1-0716-2409-8_13

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Obesity favors the classically activated, pro-inflammatory M1 type macrophages, T-lymphocytes and adipokines which increase inflammatory metabolites similar to those found in undernutrition, including GM-CSF, IFN-, TNF, IL-6 and lipopolysaccharides (LPS) [122, 126]

Its believed that damage from oxidative stress plays a critical role in memory loss ( Because alpha-lipoic acid is a powerful antioxidant, studies have examined its ability to slow the progression of disorders characterized by memory loss, such as Alzheimers disease

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