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Between July 2016 and December 2017, it played a role in at least 91 overdose fatalities, according to the Centers for Disease Control and Prevention
Whether it accumulates in tissues is unknown
Dosing starts low and increases gradually over several months to improve tolerability
You might use the upper-right quadrant of your right thigh one week, then move to the upper-right quadrant of your left thigh the next
Drugs like Orforglipron and amycretin are advancing through clinical trials
Monitoring calcium levels is important as GLP-1 therapy can affect calcium metabolism indirectly through changes in dietary habits or gastrointestinal absorption
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