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1113 Two drug classes that significantly reduce major adverse cardiovascular events (MACE) and death, regardless of the presence of T2D, are sodiumglucose co-transporter inhibitors (SGLTis) and glucagon-like peptide-1 (GLP-1) receptor agonists (RAs)

Largest effects were observed in monotherapy vs placebo/no treatment , while head-to-head comparisons did not demonstrate superiority of ALC over antidepressant drugs

Wegovys standard maintenance dose is 2.4mg, and the 7.2mg step-up dose (MHRA approved January 2026) produces 20.7% average weight loss

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It can lead to weight loss, better glycemic control, and reduced cardiometabolic risk factors

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