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The FoxO transcription factor family plays a prominent role in muscle physiological regulation, especially the FoxO3a subtype, which plays a key role in muscle autophagy, metabolic regulation, and sarcopenia occurrence by regulating the expression of autophagy-related genes (such as LC3 and BNIP3) [48]

The use of GLP-1 agonists has been associated with significant total body weight loss (fat and lean mass), with lean mass representing approximately 25% of total body weight loss [9]

Resistin: functional roles and therapeutic considerations for cardiovascular disease

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