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Conversely, although carnitine appears to normalize the metabolic pathways of VPA in acute overdose, the few clinical data that are available do not support the use of carnitine in patients with VPA-induced CNS depression

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However, insulin elevation from food intake activates opposing lipogenic (fat-storing) pathways that can blunt the peptides fat-mobilizing effects

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Bile acid malabsorption Approximately 10-20% of people develop bile acid malabsorption after gallbladder removal, a condition where excess bile acids enter the colon, causing diarrhoea