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Lipid-based nanosystems including nanoliposomal systems, LNCs, lipid nanocomplexes, LCP, and exosomes have been shown to reduce the size of melanoma tumors [133, 139, 206, 207]

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The results showed that TAC induction led to increased mitochondrial fission and apoptosis and decreased fusion with impaired respiration, while Sema treatment ameliorated this imbalance and mitochondrial respiratory dysfunction (Fig

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