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The dual mechanism produces complementary and additive weight loss effects

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The 2022 ADA guidelines also have a section dedicated to the treatment algorithm for T2D when there is a compelling need to minimize weight gain or weight loss, suggesting that a glucagon-like peptide-1 (GLP-1) receptor agonist with good efficacy for weight loss or a sodium-glucose cotransporter-2 (SGLT-2) inhibitor be considered if first-line therapy with metformin and lifestyle modifications did not lead to adequate glycemic control in the patient [20]

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That raised concerns among Austin City Council members, who never voted on the plan and felt their constituents were being unfairly targeted in the Rundberg, Riverside and Montopolis neighborhoods