semaglutide binge eating disorder Glucagon-like peptide-1receptor agonists (GLP-1 RAs), such as (Ozempic), are medications originally developed to treat type 2 diabetes. GLP-1 RAs stabilise blood glucose by stimulating insulin production and suppressing glucagon production Novel potential pharmacological approaches in

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I put together an evidence resource on what these medications do beyond weight loss, written for clinicians and curious patients alike and current as of June 2026: (don't worry, there's a TLDR simple table in the link) Randomized trials now support meaningful benefits for cardiovascular disease, chronic kidney disease, heart failure with preserved ejection fraction, obstructive sleep apnea, MASH, and more, several with their own regulatory approvals

Weight loss medications do not work independently of lifestyle

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Preclinical studies have demonstrated that the novel hepatocellular carcinoma-selective HDAC inhibitor STR-V-53 not only inhibits HDAC activity and upregulates PD-L1 expression in tumor cells but also significantly enhances CD8 + T cell infiltration

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