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Vitamin B12 helps decrease homocysteine levels in the blood which lowers the risk of heart disease and stroke

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Funding This work was supported by the National Natural Science Foundation of China (32072813), the Science and Technology Development Project of Jilin Province (20200201535JC), and the Science and Technology Research Projects of the Education Department of Jilin Province (JJKH20211140KJ)

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Reliable quantification of individual NAD metabolites and glutathione can be achieved through liquid-chromatography mass-spectrometry (LC-MS) 22 , cyclic enzymatic assays and high-performance liquid chromatography (HPLC) 2326 , but these have not been applicable for the scalable analysis of the whole redox set, especially from a single extract