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However, in certain cases evidence exists of selection at the somatic cell level after X-chromosome inactivation

Based on parents ratings, 52% of children in the methyl B 12 group responded to treatment compared to 26% of children in the placebo group (p=0.086) 2

Protocol restraint: Researchers can focus on timing and consistency instead of assuming that escalating the amount will always improve the signal

doi: 10.1007/s41669-018-0071-6 33 NaculLCLacerdaEMCampionPPhebyDM.d.L