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The standard titration schedule starts at 2.5 mg per week for 4 weeks, then increases to 5 mg per week for another 4 weeks, with subsequent increases of 2.5 mg every 4 weeks up to a maximum of 15 mg per week (Mounjaro prescribing information, Eli Lilly)

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Chemotherapy drugs Due to its antioxidant properties, ALA may interfere with the efficacy of certain chemotherapy agents, including alkylating agents and antitumor antibiotics

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2022 Dec;65(12):1925-1966

The MichaelisMenten constant (KM value) was previously measured to determine the substrate concentration at which the reaction rate is half of the maximum velocity