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[97] [98] Novo Nordisk failed to pay a required patent maintenance fee, and their patent on the chemical structure of the drug expired in 2020

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Key Takeaways Starting dose: 0.25 mg once weekly for 4 weeks (both Ozempic and Wegovy) Ozempic max: 1.0 mg weekly (approved 2024: 2.0 mg) optimised for blood sugar control Wegovy max: 2.4 mg weekly optimised for weight loss Titration duration: ~13 weeks (Ozempic) or ~1620 weeks (Wegovy) Same molecule: Both contain identical semaglutide made by Novo Nordisk Semaglutide Dosage Chart Free printable reference chart showing Ozempic and Wegovy titration schedules side-by-side

doi: 10.1590/1413-7054202448011824 110

Selenium: This mineral is a cofactor for the enzyme that allows glutathione to neutralize free radicals