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Those with liver or kidney disease might need their doses changed because these conditions can affect how B12 is processed and removed from the body

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The biodegradable, hydrophobic A polymer block comprises a polyester or poly(ortho ester), in which the polyester is synthesized from monomers selected from the group consisting of D,L-lactide, D-lactide, L-lactide, D,L-lactic acid, D-lactic acid, L-lactic acid, glycolide, glycolic acid, -caprolactone, -hydroxyhexanoic acid, -butyrolactone, -hydroxybutyric acid, -valerolactone, -hydroxyvaleric acid, hydroxybutyric acids, malic acid, and copolymers thereof and having an average molecular weight of between about 600 and 3000 Daltons

In der toxikologischen Literatur sind schwerwiegende Nebenwirkungen dokumentiert: Rhabdomyolyse: Ein Zerfall von Muskelfasern, der Proteine ins Blut schwemmt und zu akutem Nierenversagen fhren kann