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Effects of liraglutide (NN2211), a long-acting GLP-1 analogue, on glycaemic control and bodyweight in subjects with type 2 diabetes

Both trigger GH release via GHRH receptors

Two periods of 90 days of trimetazidine (60 mg/day) also increased cardiac phosphocreatine/ATP ratio in nine patients (but three patients showed a decrease), which indicated improved mitochondrial energetics [146]

When you stop, those systems revert to baseline, and weight regain follows

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While preliminary findings are promising, further research is crucial to understand their full impact