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This is exactly what my original hormone doc told me

Animals Specific pathogen-free C57BL/6J mice, aged six to eight weeks, were procured from HuaFukang BioScience Company (Beijing, China) and maintained on a 12-h light cycle with ad libitum access to food and water

Doctors are sometimes forced to prescribe alternatives that might not be as effective

Lancet 395 , 14171418 (2020)

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1419, PL-10, PLD-116, PL 14736), in trials for inflammatory bowel disease (LD1 not achieved), wound and fistulas treatment (1-7, 27, 29, 33-37) (i.e., stimulation of expression of the early growth response 1 (egr-1) gene (38), and other molecular pathways (38-42), effective alone without carrier (1-7) it has a particular effect on endothelium protection along with prominent angiogenesis (1, 43-47) and an effect on NO-system (1-7)