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doi:10.1016/j.clinbiochem.2021.04.023
In chronic kidney disease, loss of kidney epithelial cells leads to glomerulosclerosis and tubular atrophy, whereas interstitial inflammation and fibrosis result from an excess of leukocytes and myofibroblasts
Additionally, according to the VIP score, the top influential factors in our study were MDA, urea, uric acid, creatinine, TNF-, IL-1, and AFT residue which were sensitive to various treatments and could distinguish AFT treatment from others (Figure 7C)
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Lyophilized powder stored at 20C remains stable for 24+ months