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Rare cases of severe liver injury have been reported in people taking orlistat, but it's not certain that the drug caused those problems

The disparity between the risk and incidence results might also reflect the difficulties in researching cancer outcomes in communities with low overall incidence, where conclusive results necessitate large sample numbers and long-term data

Because oral peptides must pass through the GI tract and often use absorption enhancers, they can sometimes cause localized side effects like nausea or stomach upset

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Ibeas, J.I., Yun, D.J., Damsz, B., Narasimhan, M.L., Uesono, Y., Ribas, J.C., et al., Plant J