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doi: 10.1046/j.1365-2265.2003.01791.x 39 RajaramSBaylinkDJMohanS

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HFD-fed mice with obesity had significantly increased taurine-conjugated BAs, but these affects were nearly abrogated in NLRP3-deficiency (81)

It has been experimentally confirmed that ferroptosis plays an indispensable role in RP, and research on RP models has indicated that iron homeostasis regulators inhibit photoreceptor ferroptosis and prevent degeneration

4.2.15 Hederagenin Recent studies have indicated Hederagenin (HDG) can both attenuate cerebral I/R injury through the regulation of MLK3 signaling pathway (Yu et al., 2020) and enhance renal fibrosis by targeting muscarinic acetylcholine receptors (Yang and He, 2022)