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Its decline during menopause accelerates the sarcopenic trajectory that estrogen withdrawal initiates, and its restoration, where clinically appropriate, may help counteract the muscle loss that rapid weight loss compounds

Non-peptide ligands Non-peptidic agonists of GLP-1R would be desirable as therapeutic agents since they have the potential to be orally active and hence circumvent the current requirement for self-injection by patients

Diabetes Care 32(6):10461048

Make sure to always check with your doctor if you have any questions.