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126.2 g of buffer was weighed and chilled down and 24.5 g of Poloxamer 407 (Lutrol F127, BASF) were added (e.g., sprinkled) while mixing to dissolve

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--- The Human Study: What They Did The study followed patients diagnosed with chronic knee pain including osteoarthritis, patellofemoral syndrome, and post-injury degenerative changes who had not achieved adequate relief from standard interventions including physical therapy, NSAIDs, and corticosteroid injections

When combined, they form what researchers describe as a synergistic healing strategy