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However, there is no scientific evidence supporting B12 supplementation for direct fat loss in individuals with normal B12 levels

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A deficiency of vitamin B12 is fairly difficult to diagnose and there are quite a few variables that can lead to the deficiency or just not quite having enough of it regularly, so injections of vitamin B12 can benefit quite a few people who suffer from symptoms including brain fog, fatigue, lethargy, feelings of depression, tingling in their hands or feet, dizziness, and memory loss

Department of Health and Human Services Office on Womens Health

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Gastric surgery or bowel resection that has removed the part of the gut where B12 is absorbed