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This activation cascade produces pro-inflammatory cytokines, which are critical mediators of the inflammatory response

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Reducing discomfort that may lead to back pain can be achieved by consuming smaller, more frequent meals and staying away from foods that exacerbate gastrointestinal problems

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Additionally, the high expression of GPX3 may be related to the immunosuppressive state of the TME, with its expression positively associated with plasma cells and M0 macrophages and negatively associated with monocytes and M1 and M2 macrophages (Fig

3) Suppresses postprandial glucagon secretion post-meal hyperglycemia