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I got down to 800 calories a day, counting every single tiny item I put in my mouth (including gum) and exercising for 60 to 90 minutes every single day, and I lost my period, started getting dizzy spells, started getting an aversion to foods, my anxiety and depression were sky-high, and I was always feeling awful

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PLoS One 9, e103114

In addition to demonstrating the improvements in A1C illustrated in the above chart, the trials also showed improvements in other important underlying biomarkers

While severe psychiatric events are rare, related symptoms like nervousness or jitteriness are sometimes noted