The record needs to explicitly confirm that the patient is currently on a prescribed, ongoing insulin regimen
Along this line, a recent large case-control study from 2024 including 162,253 obese patients treated with GLP-1 RAs and a matched group of untreated patients found an association between GLP-1 RAs and increased risk of depression, anxiety and suicidal behavior [10]
The former is currently awaiting FDA approval for a handful of oral, daily GLP-1 agonists, while the latter is developing combination therapies that use their muscle-preserving antibodies, trevogrumab and garetosmab, alongside GLP-1 drugs like Wegovy and Ozempic, to improve fat loss while preserving muscle mass
Thats when the ICD 10 code for medication monitoring comes into play
This led to a period where GLP-1R was the primary focus of incretin-based research
From this source population, our study population was selected, consisting exclusively of individuals with at least one redeemed prescription for GLP-1a [Anatomical Therapeutic Chemical (ATC) system: A10BJ] or DPP-4i [ATC code: A10BH] for type-2 diabetes