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Biological Chemistry 402, 399423

At the cellular level, coptisine exerts dose-dependent cytotoxicity in HepG2 and 3T3-L1 cells, with IC 50 values of 64.81 g/mL and 56.48 g/mL, respectively, showing cytotoxicity only at relatively high concentrations (Yi et al., 2013)

Ferroptotic mechanisms and therapeutic targeting of iron metabolism and lipid peroxidation in the kidney

It is solely an investigational research reagent used in academic and industry laboratory research

It is a reflection of obesity as a chronic condition requiring ongoing management rather than a temporary intervention

doi: 10.3390/brainsci7020020 213 PokrishevskyE.GradL