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Sci 1997, 94, 1321513220

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Elevated levels of glycine, aspartate, and gamma-aminobutyric acid (GABA) have been detected in the lung tissue of COPD patients, while elevated arginine levels are observed in mouse modelswith these changes linked to inflammation and oxidative stress Glutamine levels exhibit variability across COPD cohorts but are generally associated with oxidative stress and nitrogen balance regulation (67)