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A drug with a core oncology indication that obtains approval for a cardiovascular use gains three years of exclusivity for that cardiovascular indication, during which time sales in that indication contribute to total revenue without generic competition

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Box plot of baseline myometry data (column 1) and change from baseline (CFB) at 6 months (column 2) and 12 months (column 3)

WHO, World Health Organization 1

Similar findings were later observed in cultured starved hepatocytes, where oxidative damage prompted the removal of damaged mitochondria to maintain mitochondrial integrity for cellular homeostasis [7]