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The protective effect of SFN appears to be NRF2-dependent, as NRF2 deficiency exacerbated psoriasis-like symptoms, as well as the inflammatory response and abnormal proliferation of keratinocytes in the mice, and SFN had little therapeutic effect in the IMQ-modeled knockout mice

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Its broad range of research applications has made it one of the most recognised peptides within regenerative and recovery-focused research models

This combination requires careful timing and may benefit from professional guidance

Azevedo, Anamelia Lorenzetti Bocca, Bruna Jacomel Favoreto de Souza Lima, Caroline Pavini Beato-Souza, Emanuel Razzolini, Sirlei G