Reported or plausible effects discussed by users and in limited literature include injection-site irritation (if used by injection), headache, nausea, fatigue, lightheadedness, and changes in sleep
In addition, frail or older patients with sarcopenia are not eligible for GLP-1RA plus SGLT2i combination therapy, as it could induce rapid and great reductions in body weight [82]
Chai W, Dong Z, Wang N, Wang W, Tao L, Cao W et al
Antioxid Redox Signal 18: 2106- 2121 Rahantaniaina MS, Li S, Chatel-Innocenti G, Tuzet A, Issakidis-Bourguet E, Mhamdi A, Noctor G (2017) Cytosolic and chloroplastic DHARs cooperate in oxidative stress-driven activation of the salicylic acid pathway
Weight loss accelerates in months two and three as appetite control deepens and your body adapts to reduced calorie intake
& Druss, B