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Up-regulation of HO-1 levels in the cell is a hallmark of oxidative stress, with downstream effects especially in the pro-oxidative state [48, 49]

When egtA is deleted and no EGT is present, a metabolic adjustment occurs whereby gliotoxin biosynthesis is decreased in order to increase GSH levels (Figure 5)

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"That was the first moment that I was like, holy cow, these insurance companies, they're now making medical decisions for me," she says